Introduction With almost 50% of cases preventable and the Australian National Bowel Cancer Screening Program in place, colorectal cancer (CRC) is a prime candidate for investment to reduce the cancer burden.The challenge is determining effective ways to reduce morbidity and mortality and their implementation through policy and practice.Pathways-Bow
A comparison of small monetary incentives to convert survey non-respondents: a randomized control trial
Abstract Background Maximizing response rates is critically important in order to provide the Hot rollers most generalizable and unbiased research results.High response rates reduce the chance of respondents being systematically different from non-respondents, and thus, reduce the risk of results not truly reflecting the study population.Monetary i
Prospects of the Use of Cell Therapy to Induce Immune Tolerance
Conditions in which abnormal or excessive immune responses exist, such as autoimmune diseases (ADs), graft-versus-host disease, transplant rejection, and hypersensitivity reactions, are serious hazards to human health and well-being.The traditional immunosuppressive drugs used to treat these conditions can lead to decreased immune function, a highe
Inhibition of malate dehydrogenase via nanoselenium coupling with nanocellulose composite in MCF-7 breast carcinoma cells
Abstract Background Cancer, a leading cause of mortality worldwide, continues to pose significant challenges in treatment and management.Conventional therapies often face limitations, including lack of selectivity, adverse effects, and the development of resistance mechanisms.Methods Therefore, this study aims to investigate nanocellulose, nanosele
Macrophages Infected by a Pathogen and a Non-pathogen Spotted Fever Group Rickettsia Reveal Differential Reprogramming Signatures Early in Infection
Despite their high degree of genomic similarity, different spotted fever group (SFG) Rickettsia are often associated with very different clinical presentations.For example, Rickettsia conorii causes Mediterranean spotted fever, a life-threatening disease for humans, whereas Rickettsia montanensis is associated with limited or no pathogenicity to hu